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Ondansetron, sold under the brand name Zofran, is typically used to treat nausea and vomiting after surgery, cancer chemotherapy, or radiation. [Ref], Very common (10% or more): Eye disorder (up to 19%), Common (1% to 10%): Visual disturbance/transient visual disturbances (e.g., blurred vision), Very rare (less than 0.01%): Transient blindness, Frequency not reported: Swollen periocular area[Ref], Cardiopulmonary arrest and shock occurred during allergic reactions in patients given the IV formulation. "Product Information. Ondansetron is a common medication that can be used to treat vomiting in dogs and cats. lorazepam, ondansetron, hydroxyzine, meclizine, promethazine, Ativan, dexamethasone, Reglan, metoclopramide, amisulpride. Bronchospasm 6. Transient, asymptomatic increases in AST/ALT 2 times the upper limit of normal commonly occurred in patients receiving chemotherapy with cisplatin, and did not appear to be related to dose/duration of treatment. It is unknown if Zofran enters breast milk. Last updated on Nov 11, 2020. [Ref], Common (1% to 10%): Injection site reactions[Ref], Rare (0.01% to 0.1%): Immediate hypersensitivity reactions (sometimes severe), anaphylaxis/anaphylactoid reactions, Frequency not reported: Poor oral intake[Ref], 1. Headache, lightheadedness, dizziness, drowsiness, tiredness, or constipation may occur. 3. Abnormal Liver Function Tests 3. [Ref], Wound problems occurred at the surgical site in patients given this drug for the treatment of postoperative nausea and vomiting. Selected from data included with permission and copyrighted by First Databank, Inc. If these effects persist or worsen, notify your doctor promptly.Remember that your doctor has prescribed this medication because he or she has judged that the … 2. It is also used to prevent or treat nausea and vomiting after surgery. Applies to ondansetron: film, solution, tablet, tablet disintegratingOther dosage forms: 1. injection solutionAlong with its needed effects, ondansetron (the active ingredient contained in Zofran) may cause some unwanted effects. Ondansetron is in a class of medications called serotonin 5-HT3 receptor antagonists. The only side effect is a headache,but it is tolerable compared to the nausea and vomiting that happen out of nowhere. Things to remember when you fill your prescription. The safety of Zofran during pregnancy is an issue in Canada as well. In the ondansetron prescribing label information (Zofran®, Zofran ODT® package insert), the most commonly reported ondansetron (Zofran®, Zofran ODT®) side effects are shown here. Ondansetron orally disintegrating tablet may cause drowsiness. Side effects. It is available in brand and generic form. Zofran (ondansetron)." WebMD does not provide medical advice, diagnosis or treatment. Cerenex Pharmaceuticals, Research Triangle Pk, NC. If experienced, these tend to have a Severe expression 1. Acute Liver Failure 5. This drug is more popular than comparable drugs. A healthcare professional should be consulted before taking any drug, changing any diet or commencing or discontinuing any course of treatment. Zofran Side Effects Include Injuries to Mothers and Babies. Cerner Multum, Inc. "Australian Product Information." Zofran (ondansetron) is an antiemetic and selective 5-HT3 receptor antagonist prescribed for the treatment of nausea and vomiting due to cancer chemotherapy and also used to prevent and treat nausea and vomiting after surgery. Call your doctor at once if you have: Abnormal Heart Electrical Signals 2. The National Institutes of Health lists the following as common side effects. It can be given by mouth or by injection into a muscle or into a vein. Prolonged QT Interval On EKG 12. More common side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them: Applies to ondansetron: injectable solution, intravenous solution, oral disintegrating strip, oral solution, oral tablet, oral tablet disintegrating, The most frequently reported side effects are headache, constipation, and diarrhea. CONDITIONS OF USE: The information in this database is intended to supplement, not substitute for, the expertise and judgment of healthcare professionals. Side Effects What are the side effects of Ondansetron (Zofran)?. difficulty with passing urine (dribbling), puffiness or swelling of the eyelids or around the eyes, face, lips, or tongue, dizziness, faintness, or lightheadedness when getting up suddenly from a lying or sitting position, increased blinking or spasms of the eyelid, large, hive-like swelling on the face, eyelids, lips, tongue, throat, hands, legs, feet, or sex organs, uncontrolled twisting movements of the neck, trunk, arms, or legs, difficulty having a bowel movement (stool), uncontrolled movements, especially of the face, neck, and back, redness of the face, neck, arms, and occasionally, upper chest. If experienced, these tend to have a Less Severe expression, If experienced, these tend to have a Severe expression. Strativa Pharmaceuticals, a Division of Par Pharmaceuticals, Inc., Woodcliff Lake, NJ. It works by blocking the action of serotonin, a natural substance that may cause nausea and vomiting. This copyrighted material has been downloaded from a licensed data provider and is not for distribution, except as may be authorized by the applicable terms of use. You may report them to the FDA. It can also cause serious skeletal defects including deformed skulls that could have an impact on the brain and cognitive development. A causal relationship to therapy with ondansetron hydrochloride has been unclear in many cases. Zofran side effects Get emergency medical help if you have any of these signs of an allergic reaction to Zofran: rash, hives; fever, chills, difficult breathing; swelling of your face, lips, tongue, or throat. [Ref], Common (1% to 10%): Sensation of warmth/flushing, bradycardia, hypotension, arrhythmias, Uncommon (0.1% to 1%): Chest pain with/without ST segment depression, Rare (0.01% to 0.1%): Transient ECG changes including QT interval prolongation (Torsade de Pointes), angina/chest pain, vascular occlusive events, tachycardia, Postmarketing reports: Cardiopulmonary arrest, shock[Ref], Common (1% to 10%): Hypoxia, lower respiratory tract disease, expectoration, cough, Rare (0.01% to 0.1%): Bronchospasm/asthma, Postmarketing reports: Shortness of breath, laryngeal edema, stridor, laryngospasm[Ref], Laryngospasm occurred during allergic reactions in patients given the IV formulation. Some other nausea medicines, the side effects ondansetron ) is a priced! To tell you about ways to prevent nausea and vomiting and side effects of Zofran in pregnant for. This drug come forward after experiencing adverse effects after taking the medication restitution for unexpected side effects with. 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